Diablo 4: Best Vampiric Powers in a Tier List

Published: Oct. 20, 2023
Updated: Oct. 20, 2023

German English

In Diablo 4 there are over 22 different Vampiric Powers. Our author, Artur Novichenko, who is a Diablo expert with more than 300 hours spent in the game, has divided them for you into his own tier list of the best Vampiric Powers in Diablo 4.

Contents of the Guide: In this guide, we're going to elaborate on the best Vampiric Powers and why you should use them. Only handpicked tips are waiting for you!

  • There are 22 Vampiric powers are divided into 4 tiers: S, A, B, and C.
  • Vampiric Powers are new in Seaoson 2 and are there to protect yourself or make the enemy vulnerable.
  • Metamorphosis, Prey on the Weak, and Hemomancy are considered the best in Diablo 4, and below we will explain in detail why.

Tier List of all Vampiric Powers in Diablo 4 Season 2

Diablo 4 Vampiric Powers Tier List

We'll start with S Tier, which contains abilities that will deal a lot of damage to enemies, so they are the best in our opinion. The next one will be A Tier, which is not as powerful, but can be very effective for most builds.

S Tier

  • Metamorphosis
  • Prey on the Weak

A Tier

  • Hemomancy
  • Sanguine Brace
  • Accursed Touch
  • Domination
  • Bathe in Blood
  • Blood Boil

B Tier

  • Moonrise
  • Terror
  • Coven’s Fangs
  • Call Familiar
  • Feed the Coven

C Tier

  • Hectic
  • Anticipation
  • Ravenous
  • Resilience
  • Flowing Veins
  • Infection
  • Jagged Spikes
  • Undying
  • Rampart

Vampiric Powers tiers aren’t just based on the damage they deal. We've organized the list by accessibility and how often a player will use a particular ability.

Read more: Diablo 4: Campaign Quest List with Descriptions

Best Vampiric Powers in Diablo 4

Let's take a look at the best Vampiric Powers in our opinion, which will be useful for any Diablo 4 player:


Diablo 4: Metamorphosis

When a player Evades, they turn into a cloud of bats and become Unstoppable for 4 seconds. During this time, enemies receive 160% Physical damage, and a Vampiric Curse is applied to them. This is one of the most useful Vampiric Powers, as it makes the player untouchable and deals a lot of damage. Metamorphosis can be obtained by completing the A Serpent Cornered quest.

Prey on the Weak

Diablo 4: Prey on the Weak

You deal 16% more damage to vulnerable enemies. Enemies become Vulnerable when they are affected by the Vampire Curse from your other vampire abilities. When combined with other abilities, these Vampiric Powers become much more powerful than it seem. Prey on the Weak is very affordable and useful. You have to spend 25 Potent Blood in the Seasonal tab to get it.


Diablo 4: Hemomancy

Your attacks deal 20% of your maximum life as physical damage to nearby enemies. This ability can be used every 4 seconds and will restore 1% of your HP for each enemy you damage. So, its advantages include fast cooldown, health recovery, and high damage, which makes Hemomancy a unique Vampiric Power. To get Hemomancy, you need to spend Potent Blood.

This was our Vampiric Powers Tier List in Diablo 4, and we sincerely hope that you will now dominate the battlefield. Enjoy!

Where to get Vampiric Powers in Diablo 4?

You can use 5 vampiric powers simultaneously and level them up to max level 3. There are several ways to get these unique powers, namely:

  • Quest of the Season 2 Questline
  • Spend Potent Blood
  • Hunter's Acclaim Board

And before you go, here we have an article, where we discuss all the unique items in Diablo 4 and their effects, make sure to check it out!

Want to join our community and discuss Diablo 4? Then feel free to join our Discord server or visit us on Facebook. We look forward to seeing you there!

Artur is our English-speaking writer from Ukraine who covers many topics in the gaming field. From indies to triple-A blockbusters, he is a gamer through and through. He has been supporting our team as a freelancer since the beginning of 2023.
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